Quick guide for analysing data with CarimasTurku

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Step 1. Load the data 
Step 2. Preprocess, reoritent and crop the data in the volume view window
Step 3. Reorient data in reorientation window
Step 4. Perform the heart's segmentation in ROI definition window
Step 5. Perform modelling in the modelling window
Step 6. Report the result
Step 7. Output the parametric volume

• Step 1. Load the data

• File->OpenFile->ECAT->Ecat7/Ecat6
• File->OpenFile->DICOM

          
                Note: CarimasTurku only works with the dynamic PET data, static data is not available for the current version.

• Step 2. Preprocess, reoritent and crop the data in volume view window

                After loading the data, the volume view window will apear automatically as shown below. Main functions of the step:

• Visualise the data.
• Make a "difference" image.
• Remove a hotspot.
• Crop the heart volume.

           

• Step 3. Reorient the data in the reorientation window

• Define the long axis: it should be drawn from the apex  to the base.
• Define the centres of left and right ventricular cavities: it should be drawn from left to right one.

           

• Step 4. Perform the heart's segmentation in the ROI definition window

• Automatic segmenation of heart ROIs.
  
• User can guide program to refine heart ROI definition using different tools.
• User can modify heart ROIs manually.

           

• Step 5. Perform modelling in the modelling window

• Special modelling and analysis of 15O-water, 13N-ammonia, 82Rb and 11C-acetate.
• General graphic analysis: Patlak, Logan and retention index, suitable for 18F-FDG and 18F-FTHA.
• Fitting quality can be visualized.
• Polarmap can be output as JPEG image.
• Segment fitting result can be output in ASCII format text file.

           

•    Step 6. Report

• Patient, study and isotopic  information.
• Modelling results.
• Polarmap
• Heart ROIs.
• 3D parametric volume.
• Analysis date and time.

           

•    Step 7. Output of parametric volume

• Only work when CarimasTurku works with GE ADW package.

           
This 3D heart of left ventricle, aorta and coronary tree is reconstructed using CTA data (GE Discovery PET-CT) by GE ADW package. The colour on left ventricular surface represents the perfusion absolute value obtained by 15O-water study. Firstly, CarimasTurku generates a heart volume based on heart ROIs and then maps polarmap flow value on the volume of heart, furthermore. CarimasTurku outputs parametric volume as DICOM format and send data back to GE ADW database for performing fuse with CTA.   

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Website is updated by Chunlei Han, last update is April 27, 2007, Turku, Finland.