Analysis of [18F]NS12137 PET data

[F-18]NS12137

[18F]NS12137 is a radiopharmaceutical that targets noradrenaline transporter (NET). NET can be used as a marker of sympathetic nervous system activity and innervation.

In preclinical studies [18F]NS12137 has been shown to be a promising radiotracer for NET imaging in the brain (Kirjavainen et al., 2018; López-Picón et al., 2019). The radiosynthesis of [18F]NS12137 is straightforward (Lahdenpohja et al., 2019).


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Literature

Kirjavainen AK, Forsback S, López-Picón FR, Marjamäki P, Takkinen J, Haaparanta-Solin M, Peters D, Solin O. 18F-labeled norepinephrine transporter tracer [18F]NS12137: radiosynthesis and preclinical evaluation. Nucl Med Biol. 2018; 56: 39-46. doi: 10.1016/j.nucmedbio.2017.10.005.



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Updated at: 2022-01-24
Created at: 2021-11-30
Written by: Vesa Oikonen