fit_pbr - tpcclib 0.7.8 © 2022 by Turku PET Centre

Non-linear fitting of a function to sampled plasma-to-blood ratio data.
 
Usage: fit_pbr [Options] datafile [parfile]
 
Options:
 -HCT=<Haematocrit>
     Constrain haematocrit to specified value; fitted by default.
 -min=<OLS|LAD>
     Sum-of-squares (OLS) is minimized by default, but optionally
     sum of absolute deviations (LAD) can be selected.
 -w1
     All weights are set to 1.0 (no weighting); by default, weights in
     data file are used, if available.
 -wf
     Weight by sampling interval.
 -k=<value>
     Parameter k is constrained to given value.
 -lim[=<filename>]
     Specify the constraints for function parameters;
     This file with default values can be created by giving this option
     as the only command-line argument to this program.
     Without file name the default values are printed on screen.
 -svg=<Filename>
     Fitted and measured TACs are plotted in specified SVG file.
 -h, --help
     Display usage information on standard output and exit.
 -v, --version
     Display version and compile information on standard output and exit.
 -d[n], --debug[=n], --verbose[=n]
     Set the level (n) of debugging messages and listings.
 -q, --quiet
     Suppress displaying normal results on standard output.
 -s, --silent
     Suppress displaying anything except errors.
 
Datafile must contain at least 2 columns, sample times and ratios,
possibly also weights as last column.
 
Example:
     fit_pbr -svg=ia765pbrat.svg ia765pb.rat ia765pbrat.fit
 
See also: fit_bpr, tacinv, tacblend, b2rbc, bpr2cpr, fit_sigm, fit_hiad
 
Keywords: curve fitting, input, blood, plasma, modelling, simulation