[Turku PET Centre] [Vesa Oikonen] [PET data analysis]

2004-09-25 http://www.turkupetcentre.net/reports/0011/

WWW Guide to PET Modelling

Introduction

• PET
• Why model?

Model development

• Tracer selection
• Comprehensive model
• Workable model
• Model validation
• Model application

Simplification of studies

• Static imaging
• Macroparameters
• No blood sampling

Models for analyzing PET data

• Compartmental models
• Reference tissue compartmental models
• Generalized compartmental modeling approaches
  • Logan plot
  • Gjedde-Patlak plot
  • Spectral analysis
  • Transient equilibrium
  • Autoradiography
• Distributed models

Which model to use?

Receptor binding

• Measuring receptor occupancy
• Estimating B_max and K_D

Vocabulary

A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W| X | Y | Z

Links to PET modeling

References to PET modelling

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