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Turku PET Centre modelling reports

1. Model equations for common compartmental models
   • Appendix A: Model equations for parallel compartmental model with additional loss rate constant
2. Model equations for reference tissue compartmental models
3. Model equations for the dispersion of the input function in bolus infusion PET studies
4. Model equations for [¹⁵O]H₂O PET perfusion (blood flow) studies
5. Model equations for myocardial perfusion studies with [¹⁵O]H₂O PET.
   • Appendix A: right ventricular region
6. Equations for graphical analysis of irreversible tracers (Gjedde-Patlak plot)
7. Equations for graphical analysis of reversible tracers (Logan plot)
8. Noise model for PET time-radioactivity curves
9. Models for plasma metabolite correction
   • Appendix A: Huang's model for plasma metabolites
   • Appendix B: Extended Carson's model for plasma metabolites
   • Appendix C: New model for plasma metabolites
10. Modelling input function
    • Appendix A: Graham's plasma time-activity curve model
    • Appendix B: Graham's plasma time-activity curve model for parent tracer and a metabolite (restricted access)
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12. Removing bias in the graphical analysis methods (for local use only)
13. Conversion of plasma TACs to blood (for local use only)
14. Quantification of myocardial perfusion using Gd-DTPA and SAT-turboFLASH MRI
15. BNCT modelling: [¹⁸F]¹⁰B-FBPA PET
16. Model averaging with Akaike weights
17. Parametric images of [¹¹C]flumazenil binding
    • Appendix A: Does heterogeneity affect [11C]flumazenil binding maps?
18. NET and [¹⁸F]FDOPA PET
19. Correction for time delay between PET and blood data (DRAFT)
20. Using NNLS in multilinear PET problems
    • Appendix A: testing NNLS algorithm
    • Test code
21. [¹¹C]NNC 756: validation of analysis method
22. Applications of wavelets in PET modelling
23. Multilinear solution for 4-compartment model: I. Tissue compartments in series
24. Multilinear solution for 4-compartment model: II. Two parallel tissue compartments
25. Using QR decomposition for overdetermined systems
    • Appendix A: testing QR algorithm
    • Test code
26. Using GLLS to overcome bias problem
27. Using basis function method for parametric mapping
    • Appendix A: Testing basis function method with program imgbfbp
28. Study on basis function methods reliance on θ₃ parameter limits
    • Study with simulated [¹¹C]raclopride images (restricted access)
    • Phantom study (restricted access)
29. Cluster analysis for dynamic PET studies
    • Pseudo-code for the clustering algorithm based on a mixture model
    • Pseudo-code for the clustering algorithm based on a least-squares distance measure
    • Pseudo-code for the Markov random field clustering algorithm
30. Modelling of [¹¹C]PE2I
    • [¹¹C]PE2I PET data (restricted access)
    • [¹¹C]PE2I compartment model fit with plasma input (restricted access)
    • [¹¹C]PE2I multiple-time graphical analysis (Logan plot) (restricted access)
    • [¹¹C]PE2I recerence tissue compartment model fit (restricted access)
    • Simulation on PVE in [¹¹C]PE2I PET studies (restricted access)
    • [¹¹C]PE2I ratio-method (restricted access)
    • [¹¹C]PE2I blood-to-plasma ratio (in intranet)
31. Modelling ADAM and MADAM
    • Appendix A: DADAM and MADAM PET study (restricted access)
    • Appendix B: DADAM and MADAM compartmental fit with plasma input (restricted access)
    • Appendix C: DADAM and MADAM multiple-time graphical analysis (Logan plot) (restricted access)
    • Appendix D: DADAM and MADAM reference tissue compartment model fit (restricted access)
    • Appendix E: DADAM and MADAM ratio-method (restricted access)
32. Analysis of renal perfusion from [¹⁵O]H₂O PET studies
    • Appendix A: time delay correction (restricted access)
    • Appendix B: Dispersion correction (restricted access)
    • Appendix C: Pixel-by-pixel calculation with and without RBV estimation (restricted access)
33. Analysis of [¹¹C]L-deprenyl-D2 brain PET studies
    • Appendix A: processing of blood data (in intranet)
    • Appendix B: blood data pharmacokinetics (in intranet)
    • Appendix C: compartment model analysis of regional data (in intranet)
    • Appendix D: compartment model analysis of image data (in intranet)
34. Solving compartment model ODEs (proposed)
35. Analysis of [¹¹C]TMSX PET studies
    • Appendix A: Literature survey (intranet)
    • Appendix B: Blood/plasma ratio (intranet)
36. Comparing equality of two time activity curves with runs test
37. Effects of decay correction in autoradiography method
    • Appendix A: Study with real [¹⁵O]H₂O PET data
38. Using modified SRTM in non-steady-state measurements
39. Model equations for myocardial perfusion studies with [1-¹¹C]acetate PET
40. Model equations for myocardial oxygen consumption studies with [¹⁵O]O₂ PET.

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