arlkup 2.1.4 © 1996-2013 by Turku PET Centre
Calculation of blood flow value look-up table from [O-15]H2O blood curve
for using with PET in vivo autoradiographic (ARG) method (1-5).
Command-line arguments must be given in this order:
1) Blood datafile (calibrated and corrected for decay),
2) Partition coefficient p [mL/mL],
3) Maximal blood flow [mL/(min*100mL)],
4) Integration start time [sec],
5) Integration duration [sec],
6) Size of the table (nr of rows),
7) Filename for the look-up table
Options:
-static=<y|N>
The look-up table integral can be corrected for physical decay as
single frame when static PET scan was performed (y), or dynamically
(N, the default).
-h or --help
Print this message and exit
--version, or --build
Print software build information and exit
--silent
Program works silently, printing only warnings and error messages
--verbose
Program prints more information about what it is doing.
Example:
arlkup s1456_blo.fit 0.8 50 0 120 5000 s1456.lkup
Times in blood datafile must be in seconds, and radioactivities in the same
units as are the calibration units of the PET image that will be converted
to the flow image.
Look-up table will contain 2 columns: integral [sec*kBq/mL] and flow
[mL/(min*100mL)].
References:
1. Raichle ME. Quantitative in vivo autoradiography with positron emission
tomography. Brain Res Rev. 1979;1:47-68.
2. Herscovitch P, Markham J, Raichle ME. Brain blood flow measured with
intravenous H215O. I. Theory and error analysis. J Nucl Med. 1983;
24:782-789.
3. Raichle ME, Martin WRW, Herscovitch P, Mintun MA, Markham J. Brain blood
flow measured with intravenous H215O. II. Implementation and validation.
J Nucl Med. 1983;24:790-798.
4. Ruotsalainen U, Raitakari M, Nuutila P, Oikonen V, Sipila H, Teras M,
Knuuti J, Bloomfield PM, Iida H. Quantitative blood flow measurement of
skeletal muscle using oxygen-15-water and PET. J Nucl Med. 1997;
38:314-319.
5.
http://www.turkupetcentre.net/analysis/doc/tracer/arg_h2o.html
See also:
imgarg,
fitdelay,
imginteg,
ecatlkup,
dftlkup,
ecatunit,
imgflow
Keywords: perfusion, autoradiography, ARG, look-up table
This program comes with ABSOLUTELY NO WARRANTY. This is free software, and
you are welcome to redistribute it under GNU General Public License.