extrapol 1.1.1 © 2003-2009 by Turku PET Centre
Extrapolates exponentially decreasing tail of PET plasma curves.
This is accomplished by fitting line to the end-part of the plot of the
natural logarithm of tracer concentration against time.
This approach may be applied to TACs which approach zero; thus this
cannot be used with tracers like radiowater.
Usage: extrapol [Options] <Plasmafile> <Last extrapolated time> <Output file>
Options:
-e[nd]=<Fit end time>
Start the search to fit end time; by default, the search for the best
line fit is started from the last sample.
-minnr=<Minimum nr of samples>
Set the minimum number of samples used in searching the best fit;
by default 3.
-maxnr=<Maximum nr of samples>
Set the maximum number of samples used in searching the best fit;
by default all.
-mintime=<Minimum time>
Set a minimum time range used in searching the best fit.
-svg=<Filename>
Measured and extrapolated TACs are plotted in specified SVG file.
-h or --help
Print this message and exit.
--version or --build
Print software build information and exit.
--silent
Program works silently, printing only error and warning messages.
--verbose
Program prints more information about what it is doing.
Plasmafile must contain a time column, and one or more concentration columns
separated by space(s) or tabulator(s). File can also be in DFT format,
http://www.turkupetcentre.net/analysis/doc/format_dft.html
The last extrapolation time must be given in same units as are the sample
times in datafile.
See also:
paucinf,
avgbolus,
fit_meb,
fit_exp,
fit_feng,
fit2dat
Keywords: input, plasma, metabolite correction, modelling, simulation
This program comes with ABSOLUTELY NO WARRANTY. This is free software, and
you are welcome to redistribute it under GNU General Public License.