fit_orm 0.4.8 © 2008-2010 by Turku PET Centre
Fits a model dedicated for ORM-B to regional PET study data.
Command line arguments:
1) Plasma parent TAC file
2) Plasma metabolite TAC file
3) Blood TAC file
4) Brain TAC file (*.dft)
5) Fit duration (min)
6) Result file
General options:
-ref=<Region name or number>
-wm=<Region name or number>
White matter region is used to account for partial volume effect
in all other regions
-SD[=<Y|n>]
Standard deviations are calculated and saved in results (y), or
not calculated (n)
-CL[=<Y|n>]
95% Confidence limits are calculated and saved in results (y), or
not calculated (n)
-svg=<Filename>
Plots of original and fitted TACs are written in specified file in
Scalable Vector Graphics (SVG) 1.1 format; specification in
http://www.w3.org/TR/SVG/
-fit=<Filename>
Fitted regional TACs are written in DFT format.
-h or --help
Print this message and exit
--version or --build
Print software build information and exit
--silent
Program works silently, printing only error and warning messages
--verbose
Program prints more of information about what it is doing
Options to set model parameters:
-Af=<Arterial proportion (%)>
Set the simulated arterial proportion of total blood volume;
default is 30%, minimum is 1%
-fixvfp[=<y|N>]
Vfp is constrained or not constrained to its estimate on reference
region, if reference region is given with option -ref
-fixmc1[=<y|N>]
mc1 is constrained or not constrained to its estimate on reference
region, if reference region is given with option -ref
-fixmc2[=<y|N>]
mc2 is constrained or not constrained to its estimate on reference
region, if reference region is given with option -ref
-fixvfm[=<y|N>]
Vfm is constrained or not constrained to its estimate on reference
region, if reference region is given with option -ref
-mc1=<value>
mc1 is constrained to specified value in all regions
-mc2=<value>
mc2 is constrained to specified value in all regions
-irreversible
Binding has an irreversible component (k4=0)
-cm=1
One-tissue compartment model is used for all regions (k3=k4=0).
See also:
rescoll,
metabcor,
dftweigh,
dftcalc,
sim_orm,
fitk4
Keywords: DFT, modelling
This program comes with ABSOLUTELY NO WARRANTY. This is free software, and
you are welcome to redistribute it under GNU General Public License.