hypotime 0.1.1 © 2009 by Turku PET Centre
Hypotime method (1) for dynamic PET images in ECAT 6.3 or 7.2 format.
This method maps the washout of PET radioligands which are very fast cleared
from circulation, as for example [C-11]WAY-100635.
Parameters:
1) Dynamic image file
2) Hypotime image file
Options:
-thr=<threshold%>
Pixels with AUC less than (threshold/100 x max AUC) are set to zero.
Default is 0 %.
-T=<time>
By default Hypotime measure is calculated at the end of last PET frame.
This option can be used to set an earlier time point.
-dt
Hypotime measure is divided by T, and then 0.5 is subtracted, resulting
into image with values between 0.0 (absent washout) and 0.5 (infinitely
high washout rate).
-h or --help
Print this message and exit.
-v, --version or --build
Print software build information and exit.
--silent
Program works silently, printing only error and warning messages.
Example:
hypotime -thr=7 -dt ua2918dy1.v ua2918ht.v
References:
1. Moeller M, Rodell A, Gjedde A. Parametric mapping of 5HT1A receptor
sites in the human brain with the Hypotime method: theory and normal
values. J Nucl Med. 2009; 50: 1229-1236.
See also:
imgbox,
imgshrink,
ecat2tif
Keywords: image, modelling, reversible uptake, hypotime method
This program comes with ABSOLUTELY NO WARRANTY. This is free software, and
you are welcome to redistribute it under GNU General Public License.