imgfur 1.0.3 © 2007-2012 by Turku PET Centre
Calculation of Fractional Uptake Rate (FUR) or FUR-based Metabolic Rate (MR)
image from static or dynamic PET image in ECAT 6.3 or 7.2 format.
Information on FUR in:
http://www.turkupetcentre.net/modelling/methods/fur.html
Parameters:
1) Input file (Plasma TAC)
2) PET image file
3-4) FUR calculation start and stop time (min);
set both to zero to use the whole time range from PET image data
5) FUR or MR image file
Options for calculation of metabolic rate:
-Ca=<value>
Concentration of native substrate in arterial plasma (mM),
for example plasma glucose in [18F]FDG studies.
With this option the metabolic rate (umol/(min*100 g)) is calculated.
-LC=<value>
Lumped Constant in MR calculation; default is 1.0.
-density=<value>
Tissue density in MR calculation; default is 1.0 g/ml.
General options:
-h or --help
Print this message and exit.
-v, --version or --build
Print software build information and exit.
--silent
Program works silently, printing only error and warning messages.
--verbose
Program prints more information about what it is doing.
Example 1. Calculation of FUR image from a dynamic image from 45 to 60 min:
imgfur ua2918ap.kbq ua2918dy1.v 45 60 ua2918fur.v
Example 2. Calculation of glucose uptake image, when tissue density is 1.04,
plasma glucose concentration is 5.2 mM, lumped constant is 0.52, from
a static (one frame) image:
imgfur -density=1.04 -Ca=5.2 -LC=0.52 a864ap.kbq a864dy1.v 0 0 a864mrglu.v
Format of the plasma data file is specified in
http://www.turkupetcentre.net/analysis/doc/format_dft.html
The unit of pixel values in the FUR image is
(mL plasma)/(min*(mL tissue)) by default, and umol/(min*100 g) in metabolic
rate image.
See also:
imgki,
imginteg,
ecatcalc,
ecattime,
ecat2tif,
regfur
Keywords: image, modelling, FUR, retention index, irreversible uptake
This program comes with ABSOLUTELY NO WARRANTY. This is free software, and
you are welcome to redistribute it under GNU General Public License.