o2metab 1.3.0 © 2002,2008 by Turku PET Centre
Calculates the blood time-activity curves (TACs) of labelled water and
oxygen from arterial blood TAC measured after [O-15]O2 bolus using
a dedicated [O-15]O2 metabolite model (1, 2) to be used as input in
oxygen-15 model.
Command-line arguments:
1) Arterial blood TAC file (corrected for decay, sample times in sec)
and optionally either:
2) Parameter file (produced by fit_o2bl version 1.2 or later)
or:
2) model parameter k1 (1/sec)
3) model parameter k3 (1/sec)
4) model parameter k4 (1/sec)
5) model parameter delay (sec)
Options:
-o2w
Simulates the blood [O-15]H2O TAC from [O-15]O2 TAC which is in this
case provided as input.
-h or --help
Print this message and exit
--version or --build
Print software build information and exit
--silent
Program works silently, printing only error and warning messages.
--verbose
Program prints lots of information about what it is doing.
Labeled oxygen and water TACs are written in the same folder than blood TAC
is, with _o and _w added in the filename before extension.
Example 1: calculation of oxygen and water curves with default model
parameters
o2metab s4455blo.kbq
Example 2: calculation of oxygen and water curves with user-specified
model parameters
o2metab s4455blo.kbq 1.307e-3 2.034e-3 0 0
Example 3: simulation of water curve from oxygen curve with default model
parameters
o2metab -o2w s4455blo_o.kbq
References:
1. Huang S-C et al. Modelling approach for separating blood time-activity
curves in positron emission tomographic studies.
Phys Med Biol. 1991;36(6):749-761.
2. Iida H et al. Modelling approach to eliminate the need to separate
arterial plasma in oxygen-15 inhalation positron emission tomography.
J Nucl Med. 1993;34:1333-1340.
See also:
fit_o2bl,
o2_p2w,
fit_mo2,
metabcor,
dft2svg
Keywords: DFT, input, blood, metabolite correction, oxygen
This program comes with ABSOLUTELY NO WARRANTY. This is free software, and
you are welcome to redistribute it under GNU General Public License.