conv1tcm - tpcclib 0.7.4 © 2019 by Turku PET Centre

Simulation of PET tissue time-radioactivity concentration curve (TAC)
from arterial plasma (Ca) TAC, based on one-tissue compartment model,
using linear discrete time convolution:
 
  ____    K1   ____    
 | Ca | ----> | Ct |   
 |____| <---- |____|   
          k2           
 
Ct(T) = K1*Ca(T) (x) exp[-k2*T]
, where (x) denotes the operation of convolution.
 
Usage: conv1tcm [Options] plasmafile K1 k2 outputfile 
 
Options:
 -i=<Interval>
     Sample time interval in convolution; by default the shortest interval
     in the plasma data; too long interval as compared to k2 leads to bias.
 -h, --help
     Display usage information on standard output and exit.
 -v, --version
     Display version and compile information on standard output and exit.
 -d[n], --debug[=n], --verbose[=n]
     Set the level (n) of debugging messages and listings.
 -q, --quiet
     Suppress displaying normal results on standard output.
 -s, --silent
     Suppress displaying anything except errors.
 
The units of rate constants must be 1/min or 1/s depending on the time units
of the plasma file, min or s, respectively.
For accurate results, plasma TAC should have very short sampling intervals.
Frame durations are not used, even if available in the TAC file.
 
Example:
     conv1tcm plasma.tac 0.4 0.5 simulated.tac
 
See also: sim_3tcm, fit2dat, tacadd, simdisp, simframe, svar4tac, fitk2
 
Keywords: TAC, simulation, modelling, compartmental model, convolution