extrapol - tpcclib 0.7.3 © 2019 by Turku PET Centre

Extrapolation of the decreasing tail of PET input curve to given time.
This is accomplished by fitting line to the end-part of the plot of the
natural logarithm of tracer concentration against time.
This approach may be applied to TACs which approach zero; thus this
works best for metabolite-corrected input TACs, and cannot be used with
tracers with very slow clearance, such as radiowater.
 
Usage: extrapol [Options] inputfile time outputfile
 
Options:
 -e[nd]=<Fit end time>
     Start the search to fit end time; by default, the search for the best
     line fit is started from the last sample.
 -minnr=<Minimum nr of samples>
     Set the minimum number of samples used in searching the best fit;
     by default 3.
 -maxnr=<Maximum nr of samples>
     Set the maximum number of samples used in searching the best fit;
     by default all samples.
 -mintime=<Minimum time>
     Set a minimum time range used in searching the best fit.
 -svg=<Filename>
     Measured and extrapolated TACs are plotted in specified SVG file.
 -h, --help
     Display usage information on standard output and exit.
 -v, --version
     Display version and compile information on standard output and exit.
 -d[n], --debug[=n], --verbose[=n]
     Set the level (n) of debugging messages and listings.
 -q, --quiet
     Suppress displaying normal results on standard output.
 -s, --silent
     Suppress displaying anything except errors.
 
Input TAC file must contain a time column, and one or more concentration
columns. The extrapolation time must be given in same units as are the sample
times in the datafile.
 
See also: paucinf, avgbolus, fit_meb, fit_exp, fit_feng, fit2dat, tacln
 
Keywords: input, plasma, TAC, modelling, simulation