fit_wpul - tpcclib 0.7.8 © 2022 by Turku PET Centre

Non-linear fitting of the radiowater model to pulmonary TTACs using BTAC
from RV cavity as the input function. Small delay and dispersion of input
function prior to lungs is allowed and fitted by default. Regional
radioactivity concentration is modelled as Cpet(t) = Vb*Cb(t) + Ct(t),
and thus the estimated K1 = (1-Va-Vb)*f. Air volume fraction (Va) could
be estimated from transmission or CT scan.
 
Usage: fit_wpul [Options] btacfile ttacfile [parfile]
 
Options:
 -tau=<value>
     Dispersion time constant is constrained to given value (sec).
 -Vb=<value>
     Blood volume is constrained to given value (mL/mL of lung).
 -w1
     All weights are set to 1.0 (no weighting); by default, weights in
     output data file are used, if available.
 -wf
     Weight by output TAC sampling interval.
 -svg=<Filename>
     Fitted and measured TACs are plotted in specified SVG file.
 -sim=<Filename>
     Fitted TTACs at BTAC sample times are saved in specified TAC file.
 -h, --help
     Display usage information on standard output and exit.
 -v, --version
     Display version and compile information on standard output and exit.
 -d[n], --debug[=n], --verbose[=n]
     Set the level (n) of debugging messages and listings.
 -q, --quiet
     Suppress displaying normal results on standard output.
 -s, --silent
     Suppress displaying anything except errors.
 
Sample times must be in seconds, unless units are specified in the file.
 
See also: fit_h2o, bfmh2o, fitk2, fit_wrlv, fit_disp
 
Keywords: TAC, modelling, perfusion, lungs, radiowater