yokoi - tpcclib 0.7.8 © 2022 by Turku PET Centre

Calculate K1, k2, and K1/k2 using multiple-time graphical analysis (MTGA)
for reversible PET ligands (Yokoi plot) (1,2,3) from regional PET TACs.
 
Usage: yokoi [options] tacfile input starttime endtime resultfile
 
Options:
 -sd=<y|N>
     Standard deviations are saved (y) or not saved (n, default) in results.
 -svg=<Filename>
     Plots are written in specified file in Scalable Vector Graphics (SVG) 1.1
     format; specification in http://www.w3.org/TR/SVG/
 -plot=<Filename>
     Data for plots is written in TSV format for easy importing in Excel
     or OpenOffice spreadsheet, where the data can be viewed.
 -h, --help
     Display usage information on standard output and exit.
 -v, --version
     Display version and compile information on standard output and exit.
 -d[n], --debug[=n], --verbose[=n]
     Set the level (n) of debugging messages and listings.
 -q, --quiet
     Suppress displaying normal results on standard output.
 -s, --silent
     Suppress displaying anything except errors.
 
References:
1. Yokoi T, Iida H, Itoh H, Kanno I. A new graphic plot analysis for cerebral
   blood flow and partition coefficient with iodine-123-iodoamphetamine
   and dynamic SPECT validation studies using oxygen-15-water and PET.
   J Nucl Med. 1993; 34(3): 498-505.
2. Ito H, Yokoi T, Ikoma Y, et al. A new graphic plot analysis for
   determination of neuroreceptor binding in positron emission tomography
   studies. NeuroImage 2010; 49(1): 578-586.
3. Ito H, Ikoma Y, Seki C, et al. Visual evaluation of kinetic
   characteristics of PET probe for neuroreceptors using a two-phase graphic
   plot analysis. Ann Nucl Med. 2017; 31(4): 273-282.
 
See also: logan, patlak, fitk2, lhsol
 
Keywords: TAC, MTGA, modelling, K1, Vt