eabaort 1.2.3 © 2005,2006 by Turku PET Centre

Extracts arterial input curve from abdominal region of a dynamic [O-15]H2O PET image by finding the aorta, and corrects it with recovery coefficient based on method by Germano et al. [1]. Diameter of the aorta is estimated from planes plane1-plane2, which must be spesified by the user! Supported file formats are ECAT 6.3, ECAT 7. In case of Analyze image input, you need to add the frame information to the blood data separately. This can be done with program dftframe. NOTICE: planes from plane1 to plane 2 should contain a clear view of the abdominal aorta (that hasn't yet split into two vessels). NOTICE: It is also recommended that the full width half maximum (FWHM) value is always spesified separately for each scanner and reconstrution method. Usage: eabaort <ECAT Image> <plane1> <plane2> <Blood file> Options: -F=<value> Set FWHM (mm) to another value than the default (10 mm). -d=<value> Set diameter (mm) of the vessel. If not given, will be estimated -t=<threshold(%)> Set threshold percentage. Default is 95% -o=<filename> Image showing which pixels were thresholded. -p=<D/B> Diameter(D) or background(B) will be estimated based on one (best) plane instead of average over several planes (default). If -p is given without parameter then both diameter and background will be estimated based on only one plane. -b=<filename> Background curve. -m=<filename> Noncorrected thresholded curve. -pixelsize=<value> Pixel size (mm) if image header does not contain it or is not correct. e.g.: eabaort -F=6.3 -t=90 s09876dy1.img 10 15 s09876ab.dat If result filename has extension .dft both frame start and end times are written in it, otherwise only frame mid times. References: 1. Germano G, Chen BC, Huang S-C, Gambhir SS, Hoffman EJ, Phelps ME. Use of abdominal aorta for arterial input function determination in hepatic and renal PET studies. J Nucl Med 1992;33:613-620. 2. Scremin OU, Cuevas-Trisan RL, Scremin E, Brown CV, Mandelkern MA. Functional electrical stimulation effect on skeletal muscle blood flow measured with H215O positron emission tomography. Arch Phys Med Rehabil 1998;79:641-646. 3. Brix G, Belleman ME, Hauser H, Doll J. Recovery-koeffizienten zur quantifierung der arteriellen inputfunktion aus dynamischen PET- messungen: experimentelle und theoretische bestimmung. Nuklearmedizin 2002;41:184-190.

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Last updated 2006-02-20 14:56:50