Water_input:
script for preprocessing [¹⁵O]H₂O input data

Script water_input (this link opens only on Internet Explorer inside TPC network. There may also appear a security warning before opening.) is meant for preprosessing of online blood sampler curves received during [¹⁵O]H₂O PET studies.

NOTICE! It only works on Windows XP.

The script calibrates and corrects the blood curve for decay, dispersion and delay:

Decay correction takes into account the possible missmatches between start time information in the blood file and in the corresponding image file. In order to do this, the script needs also the image data in addition to blood data.

Internal dispersion time constant can be given by the user. e.g. in brain studies dispersion is usually set to 5.0 (Iida et al., 1986), which is also the default.

Delay correction is done against a countrate (head) curve, or if one is not available or suitable then e.g. against average TAC over the region of interest.

Script can be used in two different modes:

By double clicking the icon in P:\bin\windows OR by writing
```
water_input.vbs
```
in command prompt one ends up with version where required files can be specified in file browser window and the success of the script is announced in a Windows dialog box.
This is an easy way if you don't have too many blood files to correct.
If one wants to build own batch files the command prompt mode can be used.
Write e.g.
```
cscript water_input.vbs /blfile:s04064_blo.lis /crfile:s04064.img.cr /imgfile:s04064dy1_mrp.img /outfile:s04064.fit 
```
in command prompt. This requires that you have copied the water_input.vbs file from P:\bin\windows into your working directory. Other option is to use the whole path in the program call.

Always use this script inside the TUCH network! Otherwise it won't be able to find the calibration file and the program executables it needs.

Valid data sets

By now the script has been validated for the following data sets:

Scanditronics blood sampler on ECAT 931 PET scanner from an adipose tissue study.
GEMS blood sampler on GE Advance PET scanner from a kidney study.
GEMS blood sampler on GE Advance PET scanner from a static (one frame) brain study
Allogg blood sampler on HR+ PET scanner from a dynamic femoral muscle (thighs) study

If other kinds of data sets are analysed, contact Kaisa Sederholm or Vesa Oikonen for validation of the script!

Water_input:script for preprocessing [15O]H2O input data

Script can be used in two different modes:

Valid data sets

References:

Water_input:
script for preprocessing [¹⁵O]H₂O input data