liverpv - tpcclib 0.7.8 © 2022 by Turku PET Centre

Input for liver models consists of two parts: portal vein and hepatic artery.
This program generates portal vein TAC from arterial TAC using the model
proposed by Munk et al. (2003).
In a pig study, Winterdahl et al. (2011) measured beta values for
[F-18]FDG (0.50), [O-15]H2O (2.17), [O-15]CO (0.10), [C-11]methylglucose
(0.57), and [F-18]FDGal (0.82).
 
Usage: liverpv [Options] arteryfile beta outputfile
 
Options:
 -i=<Interval>
     Sample time interval in convolution; by default the shortest interval
     in the data, but restricted to range 0.0001*beta - 0.02*beta;
     too long interval leads to bias.
 -si
     Output is written with sample intervals used in convolution; by default
     data is interpolated back to the sample times of the artery data.
 -h, --help
     Display usage information on standard output and exit.
 -v, --version
     Display version and compile information on standard output and exit.
 -d[n], --debug[=n], --verbose[=n]
     Set the level (n) of debugging messages and listings.
 -q, --quiet
     Suppress displaying normal results on standard output.
 -s, --silent
     Suppress displaying anything except errors.
 
Beta must be given in minutes, and optional interval in seconds.
 
Example:
  liverpv ue65ap.bld 0.50 ue65pv.bld
 
References:
1. Munk OL, Keiding S, Bass L. Impulse-response function of splanchnic
   circulation with model-independent constraints: theory and experimental
   validation. Am J Physiol Gastrointest Liver Physiol. 2003;285:G671-G680.
2. Winterdahl M, Keiding S, Sorensen M, Mortensen FV, Alstrup AKO, Munk AL.
   Tracer input for kinetic modelling of liver physiology determined without
   sampling portal venous blood in pigs.
   Eur J Nucl Med Mol Imaging 2011;38:263-270.
 
See also: liverinp, taccalc, taccat, b2plasma
 
Keywords: input, blood, TAC, modelling, simulation, liver