o2metab - tpcclib 0.7.8 © 2022 by Turku PET Centre

Calculates the blood time-activity curves (BTACs) of labelled water and
oxygen from arterial blood TAC measured after [O-15]O2 bolus using
a dedicated [O-15]O2 metabolite model (1, 2, 3) to be used as input in
[O-15]O2 model.
 
Usage: o2metab [Options] btacfile parameterfile obtacfile wtacfile
 
Options:
 -h, --help
     Display usage information on standard output and exit.
 -v, --version
     Display version and compile information on standard output and exit.
 -d[n], --debug[=n], --verbose[=n]
     Set the level (n) of debugging messages and listings.
 -q, --quiet
     Suppress displaying normal results on standard output.
 -s, --silent
     Suppress displaying anything except errors.
 
Model parameters for k3 model (k1, k1+k3, delay) or k4 model (k1, k3,
k3/k4, delay) can be given in a RES or IFT file made by program fit_o2bl.
Parameters and data units are assumed to be in seconds, in case units
are not given in the files.
 
References:
1. Huang S-C et al. Modelling approach for separating blood time-activity
   curves in positron emission tomographic studies.
   Phys Med Biol. 1991;36(6):749-761.
2. Iida H et al. Modelling approach to eliminate the need to separate
   arterial plasma in oxygen-15 inhalation positron emission tomography.
   J Nucl Med. 1993;34:1333-1340.
3. Kudomi N et al. A physiologic model for recirculation water correction
   in CMRO2 assessment with 15O2 inhalation PET.
   J Cereb Blood Flow Metab. 2009;29(2):355-364.
 
See also: fit_o2bl, sim_o2bl, o2_p2w, fit_mo2, b2t_mo2, taccalc, tac2svg
 
Keywords: input, oxygen, blood, metabolite correction