b2m_mbf 1.2.4 © 1998-2013 by Turku PET Centre
Simulation of heart LV muscle and cavity PET TACs from arterial blood TAC
using the one-tissue compartment MBF model by Iida H et al. [1, 2]
as represented in [3].
Parameters:
1) Blood H2O data
2) Flow (mL/mL/min)
3) Alpha
4) Va
5) Beta
6) Result file for muscle and LV data
Example:
b2m_mbf s3456ab.kbq 1.24 0.6 0.3 0.8 s3454.dft
For accurate results, blood input TAC should be noiseless and have very
short sampling intervals. Simulated curves can thereafter
be interpolated to represent PET frames using program fr4sim.
References:
1. Iida H, Rhodes CG, de Silva R, Yamamoto Y, Araujo LI, Maseri A, Jones T.
Myocardial tissue fraction - correction for partial volume effects and
measure of tissue viability. J Nucl Med 1991; 32:2169-2175.
2. Iida H, Rhodes CG, de Silva R, Araujo LI, Bloomfield P, Lammertsma AA,
Jones T. Use of the left ventricular time-activity curve as a noninvasive
input function in dynamic oxygen-15-water positron emission tomography.
J Nucl Med 1992; 33:1669-1677.
3. Oikonen V. Model equations for myocardial perfusion studies with [15O]H2O
PET.
http://www.turkupetcentre.net/reports/tpcmod0005.pdf
See also:
fitmbf,
b2t_h2o,
p2t_3c,
fr4sim
Keywords: myocardium, perfusion, modelling, DFT
This program comes with ABSOLUTELY NO WARRANTY. This is free software, and
you are welcome to redistribute it under GNU General Public License.
