Calculating fractional uptake rate (FUR) image

FUR image can be calculated from dynamic (multi-frame) or static (single-frame) PET image. However, plasma time-activity curve (TAC) must be measured continuously from injection time to the FUR calculation time.

Steps to compute a FUR image:

  1. If PET image is from a late-scan, then make sure that the frame times and physical decay have been corrected to the injection time instead of scan start time
  2. Make sure that radioactivity concentrations in the plasma data file and in the PET image are in the same calibration units
  3. Calculate the FUR image using imgfur. In MS Windows command prompt window or Linux/Unix terminal window enter a command constisting of (space delimited):
    1. imgfur (program name)
    2. Filename of plasma TAC
    3. Filename of PET image
    4. FUR calculation start time in minutes (0 if all PET frames are included)
    5. FUR calculation stop time in minutes (0 if all PET frames are included)
    6. Filename for FUR image
    If necessary, read more detailed information in the user help text for imgfur
  4. FUR image can then be used in SPM or regional values can be calculated as usual.

Steps to compute a MR or GU image:

Metabolic Rate (MR) or glucose uptake (GU) image can be calculated as above, except that the following information must be given to imgfur on the command line:

If necessary, read more detailed information in the user help text for imgfur.


See also:


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