Targets of functional imaging

Metabolism
Perfusion (blood flow)
Neurotransmitter systems
Infection and inflammation
Protein deposits (proteinopathies)
Organs and tissues


References:

Alam IS, Arshad MA, Nguyen Q, Aboagye EO. Radiopharmaceuticals as probes to characterize tumour tissue. Eur J Nucl Med Mol Imaging 2015; 42: 537-561.

Cumming P, Vasdev N. The assay of enzyme activity by positron emission tomography. Neuromethods 2012; 71: 111-135.

Holland JP, Cumming P, Vasdev N. PET radiopharmaceuticals for probing enzymes in the brain. Am J Nucl Med Mol Imaging 2013; 3(3): 194-216.

Neumann K, Flavell R, Wilson DM. Exploring metabolism in vivo using endogenous 11C metabolic tracers. Semin Nucl Med. 2017; 47: 461-473.

Sosuke Miyoshi, Keisuke Mitsuoka, Shintaro Nishimura and Stephan A. Veltkamp (2011). Radioisotopes in Drug Research and Development: Focus on Positron Emission Tomography, Radioisotopes - Applications in Bio-Medical Science, Prof. Nirmal Singh (Ed.), ISBN: 978-953-307-748-2, InTech, doi: 10.5772/22728.

Vāvere AL, Scott PJH. Clinical applications of small-molecule PET radiotracers: current progress and future outlook. Semin Nucl Med. 2017; 47: 429-453.

Wong DF, Gründer G, Brasic JR. Brain imaging research: Does the science serve clinical practice? Int Rev Psychiatry 2007; 19(5): 541-558. (PubMed)



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Created at: 2007-10-22
Updated at: 2017-10-30
Written by: Vesa Oikonen