Regional Time-radioActivity Curves (TACs)
Datafiles are in ASCII format (File format (DFT) of time-radioactivity curves), that can be imported for example to Excel or Origin. See also plotting of TACs.
Calculation of regional TACs from dynamic PET images
Software for processing TACs
Editing TACs
- Combining the regions from two DFT files into one file: dftadd
- Catenating TACs, e.g. for combining early and late measurement data: dftcat
- Removing overlapping samples: dftrmovl
- Extracting specified sample time interval from the TACs: dftcut
- Extracting all or selected TACs from DFT file: dftbreak and dftadd
- Decay correction: dftdecay and dfttime; more about physical decay
- Manual time delay correction: dfttime
- Deleting selected regions from a set of TACs: dftdel
- Printing or setting the PET time frames of regional TACs: dftframe
- Adding weighting information to a DFT file: dftweigh
- Removing negative concentrations in DFT files: dftrmneg
Editing or viewing header information
- Listing the regional TACs contained in a DFT file: dftlist
- Listing the maximum value inside one or several DFT files: dftmax
- Changing the region names inside DFT file: dftren , dftvncor , and dfthncor
- Changing the study number inside DFT file: dftstudy
- Sorting regional TACs inside DFT files by name of region: dftsort
- Setting or conversion of calibration and time units in DFT file: dftunit, min2sec and sec2min.
- Removing the comments inside DFT files: dftrmcmt
Programs for converting TAC files to other formats
- Converting DFT files to simple
datafiles without titles:
dft2dat,
and the other way around with dftadd - Converting DFT files to result file format: dft2res
- Converting blood, plasma and tissue data files into PMOD format: dft2pmod
- Converting blood and plasma data files into Hammersmith format and back: dft2if, if2dft
- Converting tissue data files into Hammersmith format and back: dft2idwc, idwc2dft
- Converting DFT file into HTML table format for viewing in web browsers or importing to Excel: dft2html
- Convert regional time-activity curve (TAC) data from GEMS Xeleris to DFT format: xel2dft
- Convert regional TAC data from Vinci to DFT format:
save TACs as*.cptfiles in Vinci, and convert CPT format to DFT using cpt2dft - Convert regional TAC data from
Amide
*.tsvfiles to DFT format: tsv2dft - Converting DFT file into RFIT 4.4 format: dft2rfit
- Dynamic or parametric polar map can be converted to/from DFT file using programs pm2dft and dft2pm
- Convert CSV (comma-separated values) file in DFT format. CSV files can be saved for example in Excel.
Programs for converting TAC files from/to old format:
- Converting DFT files to
*.roi.kbqfiles: dft2nci - Converting
*.roi.kbqfiles to DFT files: nci2dft - Changing the radioactivity unit of old
*.ncifiles (nCi/mL) to*.kbq(kBq/mL): nci2kbq (available only on SUN) - Converting DFT files to
*.cptfiles: dft2cpt - Converting *.cpt files to DFT files: cpt2dft
Simple calculations with TACs
- Averaging regional TACs inside one file: dftavg
- Weighted average of all TACs ("head curve"): dfthead
- Performing simple arithmetic operations for regional TACs: dftcalc
- Subtracting a reference region TAC from other TACs: dftbound
- Calculation of sample mean
over time: dftlevel,
or mean weighted by time frame lengths:
dftinteg with option
-avg - Calculation of TAC AUC: dftinteg
- Correction of recovery and spill-over in myocardial TACs: heartcor
Fitting functions to TACs
- Exponential functions: fit_exp
- Rational functions: fit_ratf
- Sigmoidal functions: fit_gvar, fit_hiad, fit_sigm
- Calculation of TACs from function parameters: fit2dat
